Plants synthesize an amazing diversity of specialized metabolites, estimated between 200,000 to 1,000,000 metabolites in the plant kingdom and ~3,000 in each individual species. Despite a growing understanding of biosynthetic mechanisms of many specialized metabolites, the in-planta function of the vast majority remains unknow. We are interested in examining the functions of specialized metabolites in the plants that synthesize them naturally, with an emphasis on protection from herbivory, and functions in a natural setting. In such a setting, we may examine complex interactions including several trophic levels and discover interactions that we didn’t previously hypothesize.