Dissertation Topics

Prof. David Engelberg
Developmental Mechanisms of inflammatory Diseases & Cancer
Sturctual & Molecular Biochemistry
  1. Development of intrinsically active variants of the MAP kinases p38 and ERK.
  2. Revealing the mechanisms of activation of p38 and ERK through the use of the engineered active variants.
  3. Revealing the specific roles of ERK1 and ERK2 in cancer in cell lines and in transgenic mice.
  4. Revealing the specific role of p38 in chronic inflammatory diseases in cell lines and in transgenic mice.