Dissertation Topics

Prof. Yosef Gruenbaum
The Nuclear Lamina in Health and Disease
  1. The mechanical basis of lamin-based muscle and aging diseases.
  2. Regulation of cell size and metabolism by lamin and ATX-2.
  3. Regulation of chromatin organization by the lamin-binding LEM-domain and SUN-domain proteins.
  4. The regulation of mechano sensing and mechano response by emerin and UNC-84.