Post-transcriptional gene regulation during embryogenesis: mapping regulation in time and place, and learning its functional and physiological implications.
The regulation of maternally deposited RNAs during the maternal-to-zygotic transition, a key developmental transition in early embryos that is shared in all animals and initiates within transcriptionally silent embryos.
Principles of post-transcriptional RNA regulation: How does it shape gene expression? What are the molecular circuits that implement them? What is the regulatory code that defines their activity?