Dissertation Topics

Dr. Daphna  Nachmani
Translation regulation by RNA modifications in development and disease
  1. The role of RNA modifications in translation regulation – how rRNA modifications control ribosome function and its translational capacity?
  2. Hematopoiesis – We aim to understand how translation-regulation, by the ribosome, controls hematopoietic stem cell function and the generation of blood cells.  
  3. Ribosome hijacking during Viral infection – We explore how pathogens, like viruses, utilize the host’s ribosome to their own advantage to facilitate viral replication and disease manifestation.