Speaker: Prof. Eli Eisenberg, School of Physics and Astronomy and Sagol School of Neuroscience, TAU
Title: Extreme transcriptome plasticity in cephalopods: an alternate route to complexity?
Speaker: Prof. Daniel Riveline, University of Strasbourg
Title: Self Organisation of Organoids: Experiments and Theory
Speaker: Prof. Avigdor Eldar, Faculty of Life Science, Tel-Aviv University
Title: The Complexity of Decision Making in Temperate Bacteriophages - Host, Population and Environment
Speaker: Dr. Shani Levy, School of Marine Sciences, University of Haifa
Title: Every Cell Counts: Mapping Coral Biology at Cellular Resolution
Speaker: Mr. Gal Keshet, Prof. Benvenisty's Lab, HUJI
Title: Studying Pluripotency and Parental Imprinting Utilizing Human Pluripotent Stem Cells
Speaker: Prof. Roy Kishony, Faculty of biology, Technion
Title: Predicting Antibiotic Resistance
Speaker: Prof. Yehu Moran, department of Ecology, Evolution & Behavior, Inatitue of Life Sciences, HUJI
Title: Venoms that speak: Communication and conflict among animals through peptide toxins in marine ecosystems
Speaker: Prof. Karen Avraham, Gray Faculty of Medical & Health Sciences, TAU
Title: Gene Discovery and Therapy for Deafness: Advances and Challenges
Speaker: Phd Liat Morciano, Prof Giora Simchen's and Prof Ayelet Arbel's Lab, HUJI
Title: Enhanced mutagenicity in yeast meiosis resulting from DNA repair
The Seminar Will be in Hebrew
Speaker: Dr. Leonid Peshkin, Systems Biology, Harvard Medical School
Title: From Frog Pond to Clinic: Characterizing Elusive Disease-Causing Proteins and Cells
Abstract: A fundamental challenge in biomedicine is the existence of "missing" proteins—predicted by the genome but elusive in human tissue samples, potentially hiding key mechanisms of disease. To solve this, we require not just a catalog of molecules, but an organized "periodic table" of cell types, mapping their molecular identities across development to pinpoint where and when these proteins function. Leveraging the experimental power of the Xenopus frog, we have built the foundation for such a resource. We first performed a comprehensive proteomic analysis of 25 adult tissues, quantifying over 15,000+ proteins to define tissue-specific expression patterns and identify conserved and missing proteins. To complement this, we have constructed a comprehensive single-cell transcriptomic atlas spanning embryonic development and the adult organism, providing a systematic classification of cell types and states. This integrated map allows us to move from simply observing protein presence to understanding their cellular origin. Our future work will leverage this foundational atlas to characterize, at single-cell resolution, the phased emergence of the immune system in the developing frog. This focused effort will directly illuminate the cellular context of elusive immunoregulatory proteins, bridging a critical gap between early development and adult function. Referencing this resource we aim to identify tangible targets for clinical insight.